Methylation: Immune support you need

Methylation: Immune support you need

By Shannan Garrison


Boosting your immunity is likely top of mind to stay healthy. We want to talk about methylation and how it supports your immunity.

You may be asking what methylation is.

Methylation is the making of methyl groups which your body needs to be at its best. Methyl groups are necessary to turn each system on and off and help your body function properly.

One system it affects is your immune system.
Your body takes the food you eat and converts it into methyl groups. This takes time and energy and, sometimes, your body can’t do this properly. You can shortcut this process when you take methylated vitamins; with them your body isn’t required to work extra hard to change the vitamins or food you eat into a version with methyl groups. That’s because methylated vitamins come with methyl groups that are ready to go.

Our supplements are made with methylated vitamins like methylfolate (B9), methylcobalamin (B12), and pyridoxal-5-phosphate (B6), the active-form of nutrients found naturally in your body. Having extra methyl groups at your immune system’s disposal can help it work efficiently without wearing you down. 

As well as affecting your immune response, methylation also affects:

Memory   •   Mood   •   Sleep


With poor methylation, your brain, gut, and liver can’t work efficiently. This can lead to consequences such as fatigue, brain fog, mild depression, mild anxiety, and more.

Stress, lack of sleep, and age are some of the reasons why your methyl groups may be depleted. In addition, if you have the MTHFR gene variant (affects approximately 60% of people) then your body is not making enough 5-MTHF (an important enzyme for methylation) so you have fewer methyl groups in your body ready to be called into action. So, it is extremely important for you to take methylated vitamins to boost your stores up.

You can find methylated vitamins in our entire multivitamin line including Best Nest Multi+ line, Mama Bird Prenatal Multi+ line, and the Ready, Set, Go Fertility line. If you need even more, we’ve got you covered with Smart Folate.

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